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Plant-derived antioxidants: significance in skin health and the ageing process

Summary paraphrased from the peer-reviewed preclinical literature

In addition, some natural products play an important role in inducing ferroptosis in tumor cells (Table 4)

PMID: 2185038 The effect of some antineoplastic agents on glutathione S-transferase from human erythrocytes

More importantly, the downregulation of the EZH2 gene leads to a decrease in LAT1 ( SLC7A5 ) expression, and, in turn, the downregulation of LAT1 ( SLC7A5 ) or the depletion of essential amino acids can also induce a decrease in EZH2 expression (Dann et al., SLC7A5 ) indicates the potential of LAT1 ( SLC7A5 ) as a target for cancer therapy (Hafliger and Charles, In addition to regulating epigenetic methylase activity, metabolism also affects epigenetic enzymes involved in demethylation in cancer cells

Presentation of autoantigens via MHC complex/self-peptide complexes by APC and recognized in the periphery by thymus-selected autoreactive CD4 + T cells is the initial step in the pathogenesis of AITDs (82)